Sites of action of procaine at the motor end-plate.
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Substructure of Amphibian Motor End Plate
End-plate membrane has been examined at amphibian myoneural junctions by means of transmission electron microscopy of thin tissue sections. The postjunctional membrane exhibits morphologically specialized dense, convex patches which are located superficially facing the axon terminal but do not extend into the depths of the junctional folds. In the specialized regions the plasma membrane is appr...
متن کاملThe action of procaine and procaine amide on the heart.
The depressant action of procaine on the heart muscle has been the subject of several clinical and experimental studies (Wiggers and Wegria, 1940; Burstein, 1946; Uhley and Wilburne, 1948; Schaffer et al., 1950). Procaine was found useful in the treatment of cardiac arrhythmias occurring in anesthetized patients during cardiac surgery. However, its usefulness in the management of clinical arrhy...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1983
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1983.sp014524